For inside the house, I'm really been looking at the Judge. No way would I think about walking down a hallway in the middle of the night with dark rooms on either side, no time to swing it. One shot of bird shot to face will stop most people for a little awhile. Judge would work good in the back yard for Chipmonks, skunks and racoons, up to maybe 30-50ft. Op is right in that with his requirements, no gun is fit all the requirements. Fot the bigger stuff I'd just grab on of the 30 cal's with the 30 rd mag - but he wants a handgun, sounds like a wide open field there.
Dave